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DCIS and LCIS

 

Many breast cancers being found are very early cancers known as breast cancer in situ or noninvasive cancer. Most of these cancers are found by mammography. These very early cell changes may become invasive breast cancer. Two types of breast cancer in situ are:

 

DCIS (ductal carcinoma in situ), which means that abnormal cells are found only in the lining of a milk duct of the breast. These abnormal cells have not spread outside the duct. They have not spread within the breast, beyond the breast, to the lymph nodes under the arm, or to other parts of the body. There are several types of DCIS. If not removed, some types may change over time and become invasive cancers. Some may never become invasive cancers. (DCIS is sometimes called intraductal carcinoma.)

LCIS (lobular carcinoma in situ), which means that abnormal cells are found in the lining of a milk lobule. Although LCIS is not considered to be actual breast cancer at this noninvasive stage, it is a warning sign of increased risk of developing invasive cancer. LCIS is sometimes found when a biopsy is done for another lump or unusual change that is found on a mammogram. Patients with LCIS have a 25 percent chance of developing breast cancer in either breast during the next 25 years.


Specific Patterns of Breast Cancer

STAGE 0 - Very early breast cancer. This type of cancer has not spread within or outside the breast. It is sometimes called DCIS, LCIS, or breast cancerin situ or noninvasive cancer. STAGE 1 - The cancer is no larger than about 1inch in size and has not spread outside the breast. (Also described as early breast cancer.)

STAGE II

  • The cancer is no larger than 1 inch, but has spread to the lymph nodes under the arm.

  • The cancer is between 1 and 2 inches. It may or may not have spread to the lymph nodes under the arm.

  • The cancer is larger than 2 inches, but has not spread to the lymph nodes under the arm.

STAGE III is divided into stages IIIA and IIIB: The doctor may find either of the following:

  • The cancer is smaller than 2 inches and has spread to the lymph nodes under the arm. The cancer also is spreading further to other lymph nodes.

  • The cancer is larger than 2 inches and has spread to the lymph nodes under the arm.

The doctor may find either of the following:

  • The cancer has spread to tissues near the breast (skin, chest wall, including the ribs and the muscles in the chest).

  • The cancer has spread to lymphnodes inside the chest wall along the breast bone.

STAGE IV - The cancer has spread to other parts of the body, most often the bones, lungs, liver, or brain. Or, the tumor has spread locally to the skin and lymph nodes inside the neck, near the collarbone. Inflammatory Breast Cancer - Inflammatory breast cancer is a rare, but very serious, aggressive type of breast cancer. The breast may look red and feel warm. You may see ridges, welts, or hives on your breast; or the skin may look wrinkled. It is sometimes misdiagnosed as a simple infection. Recurrent
Breast Cancer -Recurrent disease means that the cancer has come back (recurred) after it has been treated. It may come back in the breast, in the soft tissues of the chest (the chest wall), or in another part of the body.

 

 

 

MICROCALCIFICATIONS

Microcalcifications are very small specks of calcium that can't be felt, but can be seen on a mammogram. They are formed by rapidly dividing cells. When they are clustered in one area of the breast, this could be an early sign of breast cancer in situ. About half of the breast cancers found by mammography appear as clusters of microcalcifications. The other half appear as lumps.

To be sure that you have a correct diagnosis if breast cancer in situ is detected, an experienced pathologist should examine your biopsy slides. You may want to have yourslides examined also by a second pathologist at a university hospital, cancer center, or breast clinic. This is important because it is sometimes difficult to make an accurate diagnosis. The pathologist needs to determine the types of cells that are present in the tissue sample, how fast the cells are changing, and whether it is likely to become invasive cancer. The diagnosis will help your doctor decide on the appropriate treatment from a wide range of choices. The decision could be to have frequent followup exams to watch the suspicious area, or surgery to remove only the affected tissue, or surgery to remove one or both breasts. Surgery removing only the affected area is sometimes followed by radiation therapy to the breast. 
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